There are over 100 identified cannabinoids out there, but most people are only aware of THC and CBD oil.
But what is CBDV?
Most cannabinoids have very similar molecular structures, but slight changes in atoms and bonds can have a huge impact on how these compounds interact with the human body.
Think of cannabinoids like keys. Keys might look similar from a distance, but look closely and you’ll see important differences in the ridges and grooves.
It’s these ridges and grooves that ensure your house key is the only one that can unlock your front door.
Cannabinoids function in a similar way. The shape and structure determine how they interact with the endocannabinoid system and how this affects us.
While THC binds to cannabinoid receptors, CBD changes the shape of receptors which alters their binding affinity.
CBDV is yet another cannabinoid that you might spot in composition analysis certificates. It is often found in very low concentrations, but research is ongoing into how this compound works and how it might help us.
What's in this Guide?
What is CBDV?
CBDV is also known as Cannabidivarin. It was identified for the first time in 1969 by researchers in Germany. CBDV is a homolog of CBD, which means it has a similar structure.
CBDV is often a very minor part of the cannabinoid profile, but some strains of C. indica landrace are naturally higher in this compound. These strains, which are often found in Asia and Africa, are also naturally low in THC.
CBDV has shown promise as an anticonvulsant and is currently under development by GW Pharmaceuticals. This organisation is pioneering cannabinoid research and development.
They are also responsible for the cannabinoid medications Sativex and Epidylex.
In a press release, GW Pharmaceuticals revealed the results of their phase 2a study. Their cannabinoid product, GWP42006, which contains CBDV as the primary cannabinoid, was part of a study into focal seizures and autism spectrum disorders.
Does CBDV Get You High?
No, like CBD, it is non-psychoactive which means it does not get you high.
Since most drugs tests are looking for the presence of THC, it also won’t show up in drug testing.
While there is a lot we don’t know about cannabinoids, we know that the majority do not have the capacity to alter your mental state. Any CBD seller trying to promote these qualities is either lying or selling an illegal product.
As CBDV is not a widely available supplement, it’s important to approach any seller offering unique cannabinoids with caution.
This is still a very unregulated market, and as such, it is prime territory for scammers looking to get rich quick.
Is CBDV Legal?
Yes, since CBDV is non-psychoactive, it is not a controlled drug. This was confirmed by a Home Office representative in a Freedom of Information request.
Only THC and its derivatives and analogues would be considered to be controlled substances.
While CBDV may be legal, it’s important to source your cannabinoid supplements from a reputable source. If your CBDV contains high levels of THC, this would be a controlled substance.
Without a testing laboratory at your disposal, you’ll have to rely on companies being honest and reliable with their testing.
Always confirm that your cannabinoid products have been tested by a third-party laboratory and that the certificate of analysis is up-to-date.
What are the Benefits of CBDV?
CBDV has been the subject of a few limited trials in animals and humans. These have focussed on the following conditions:
- Rett Syndrome
- Duchenne muscular dystrophy (DMD)
- Autism spectrum disorder (ASD)
In 2012, CBDV was the subject of a study into cannabinoids as an anticonvulsant.
The study in rats found that CBDV had significant anticonvulsant effects while having no effect on motor function.
Rett syndrome is a condition caused by a mutation on the X chromosome. It causes seizures, speech problems and muscle spasticity.
An animal study in the Journal of Psychopharmacology found that CBDV was able to rescue memory defects in mice with the same genetic defect seen in individuals with Rett syndrome.
In a 2018 study in rodents, CBDV was found to help with neurobehavioural issues associated with Rett Syndrome.
Duchenne muscular dystrophy is a disease that causes chronic inflammation and damage to the skeletal muscle. A study published in 2019 found that CBDV could prove effective in reducing inflammation and also helping to restore lost muscle mass.
Autism spectrum disorder (ASD) and childhood intractable epilepsy are often seen together.
CBDV could provide a potential treatment for some of the more severe symptoms of ASD including repetitive behavioural problems, communication, social functioning issues and cognitive issues.
And finally, it is thought that CBDV could be a powerful anti-nausea agent. In rodent tests, CBDV was found to act as an agonist for CB1 receptors which function to block nausea response.
Should I Take a CBDV Supplement?
We don’t yet know enough about CBDV to know if it is worthwhile adding to your daily routine.
More research is needed into the potential benefits of adding CBDV to CBD, in what proportions, how often and in what dosage.
Any reports that CBDV is a supplement to watch are merely anecdotal and should be taken with a grain of salt.
As the cannabinoid market matures, we expect to see far more cannabinoid isolates cropping up with new promises and selling points.
For now, anyone curious about cannabinoids would be wise to seek out a reputable CBD supplier, such as Evopure. This will ensure you are enjoying a premium-quality CBD oil with no hidden extras.